(1) gwiritsani ntchito "njira yaukadaulo" pogula zida, njira zake ndi izi. Zofunika bwino, kudziwa kusankha ndi kugula zida - chandamale ogwira ntchito zambiri (zidziwitso zikuphatikizapo: ndondomeko ntchito, cholinga kasamalidwe, kukula kwa kupanga ndi kasamalidwe boma, etc.) - chandamale mankhwala anali kusanthula, kusanthula chandamale mankhwala chandamale, ndiye gulu ntchito, yeniyeni ndi omveka ntchito, ndiye, kusanthula zida ntchito ndi digiri yofananira ya kufunika kwenikweni, kuganizira zipangizo ntchito, kukambirana njira zothandiza gulu, ndi kusanthula gulu njira kusanthula ndi kusanthula akatswiri njira zina) ubwino ndi kuipa kwa zipangizo kuchita kusanthula mtengo ndiyeno, kuphatikiza chinthu chofunika, ndi kusanja), kudziwa chandamale kusankha ndi kugula.

(2) kukhazikitsa ndi kuvomereza zida za mankhwala. Mosamalitsa molingana ndi zofunikira za GMP ndi njira zina zogwirira ntchito pakukhazikitsa ndi kuvomereza zida zamankhwala. Ophunzira akuphatikizapo: kupanga, uinjiniya, mphamvu, QA ndi akatswiri akunja. Njira yeniyeni ndi: kutsimikizira kukhazikitsa, kutsimikizira ntchito. QA ili ndi udindo wowunika ndikutsimikizira pulojekiti ya GMP, kufufuza ndi kutsimikizira.

(3) kupanga chidziwitso. Malinga ndi buku laukadaulo la zida ndi GMP, funsani akatswiri oyenerera, phatikizani tebulo lokonzekera zida ndi buku laukadaulo, ndikulemba mwatsatanetsatane zomwe zidachitika kale, njira zokonzera ndi kukonza, kuti mulimbikitse kudziwitsa komanso kukhazikika kwa kasamalidwe ka zida zamankhwala ndi kukonza.

(4) kukhazikitsa dongosolo la "magawo awiri". Monga momwe kasamalidwe ka zida za mankhwala amadziwika ndi ukatswiri wamphamvu, zovuta zovuta komanso magawo osiyanasiyana, komanso kudzidzimutsa ndi kubisala kulephera kwa zida, zimafunikira kuti tikhazikitse ntchito yofulumira komanso yogwira ntchito, njira yoyankhira komanso kuthana ndi zolephera munthawi yake. Chidule cha Shift (chikutanthauza kugwiritsa ntchito mphindi 10 musanapite kuntchito tsiku lililonse, kufotokozera mwachidule ndi kukambirana 1 d musanagwire ntchito ndi ndondomeko ya ntchito ya tsiku lino) ndi msonkhano wamlungu ndi mlungu wa dipatimenti (kuyang'ana, kubwereza ntchito sabata ino, sabata ino kuti tikambirane za mavuto akuluakulu, kukambirana za yankho, ndi kukhazikitsa ndondomeko ya ntchito sabata yamawa), yomwe ingathe kupititsa patsogolo kukhazikika kwa ntchito yobisika, ndi yofunika kwambiri kuti muchepetse chitetezo chobisika.